BDBM50529764 CHEMBL4459160

SMILES Cc1ccc(cc1-c1ccc2c(n[nH]c2c1)-c1cnn(c1)C1CCOC1)C(=O)Nc1cccc(c1)C(F)(F)F

InChI Key InChIKey=YHFMRNMPLNTYGD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50529764   

TargetFibroblast growth factor receptor 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50529764(CHEMBL4459160)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of FGFR1 (unknown origin) after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDiscoidin domain-containing receptor 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50529764(CHEMBL4459160)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of DDR2 (unknown origin) using poly (Glu, Tyr) 4:1 substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50529764(CHEMBL4459160)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of FGFR1 (unknown origin) after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDiscoidin domain-containing receptor 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50529764(CHEMBL4459160)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of DDR2 (unknown origin) using poly (Glu, Tyr) 4:1 substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed