BDBM50529757 CHEMBL4436086

SMILES Oc1cccc(Nc2nc(\C=C\c3cc4OCOc4cc3Br)nc3ccccc23)c1

InChI Key InChIKey=YVXSYYKMNOMLIT-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50529757   

TargetProtein-tyrosine kinase 6(Human)
University of Silesia In Katowice

Curated by ChEMBL
LigandPNGBDBM50529757(CHEMBL4436086)
Affinity DataIC50: 956nMAssay Description:Inhibition of BRK (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase CSK(Human)
University of Silesia In Katowice

Curated by ChEMBL
LigandPNGBDBM50529757(CHEMBL4436086)
Affinity DataIC50: 402nMAssay Description:Inhibition of CSK (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Silesia In Katowice

Curated by ChEMBL
LigandPNGBDBM50529757(CHEMBL4436086)
Affinity DataIC50: 897nMAssay Description:Inhibition of SRC (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProtein-tyrosine kinase 6(Human)
University of Silesia In Katowice

Curated by ChEMBL
LigandPNGBDBM50529757(CHEMBL4436086)
Affinity DataIC50: 956nMAssay Description:Inhibition of BRK (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Silesia In Katowice

Curated by ChEMBL
LigandPNGBDBM50529757(CHEMBL4436086)
Affinity DataIC50: 897nMAssay Description:Inhibition of SRC (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
University of Silesia In Katowice

Curated by ChEMBL
LigandPNGBDBM50529757(CHEMBL4436086)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of Lyn B (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
University of Silesia In Katowice

Curated by ChEMBL
LigandPNGBDBM50529757(CHEMBL4436086)
Affinity DataIC50: 287nMAssay Description:Inhibition of BTK (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
University of Silesia In Katowice

Curated by ChEMBL
LigandPNGBDBM50529757(CHEMBL4436086)
Affinity DataIC50: 287nMAssay Description:Inhibition of BTK (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
University of Silesia In Katowice

Curated by ChEMBL
LigandPNGBDBM50529757(CHEMBL4436086)
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of LCK (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
University of Silesia In Katowice

Curated by ChEMBL
LigandPNGBDBM50529757(CHEMBL4436086)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of Lyn B (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
University of Silesia In Katowice

Curated by ChEMBL
LigandPNGBDBM50529757(CHEMBL4436086)
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of LCK (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase CSK(Human)
University of Silesia In Katowice

Curated by ChEMBL
LigandPNGBDBM50529757(CHEMBL4436086)
Affinity DataIC50: 402nMAssay Description:Inhibition of CSK (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed