BDBM50529755 CHEMBL4476482

SMILES COc1ccccc1\C=C\c1nc(Nc2ccc3OCOc3c2)c2ccccc2n1

InChI Key InChIKey=OVDBDNFZYMESOZ-UHFFFAOYSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50529755   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Silesia In Katowice

Curated by ChEMBL
LigandPNGBDBM50529755(CHEMBL4476482)
Affinity DataIC50: 209nMAssay Description:Inhibition of SRC (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
University of Silesia In Katowice

Curated by ChEMBL
LigandPNGBDBM50529755(CHEMBL4476482)
Affinity DataIC50: 515nMAssay Description:Inhibition of LCK (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
University of Silesia In Katowice

Curated by ChEMBL
LigandPNGBDBM50529755(CHEMBL4476482)
Affinity DataIC50: 182nMAssay Description:Inhibition of ABL1 (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase CSK(Human)
University of Silesia In Katowice

Curated by ChEMBL
LigandPNGBDBM50529755(CHEMBL4476482)
Affinity DataIC50: 706nMAssay Description:Inhibition of CSK (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fyn(Human)
University of Silesia In Katowice

Curated by ChEMBL
LigandPNGBDBM50529755(CHEMBL4476482)
Affinity DataIC50: 191nMAssay Description:Inhibition of Fyn A (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
University of Silesia In Katowice

Curated by ChEMBL
LigandPNGBDBM50529755(CHEMBL4476482)
Affinity DataIC50: 182nMAssay Description:Inhibition of ABL1 (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
University of Silesia In Katowice

Curated by ChEMBL
LigandPNGBDBM50529755(CHEMBL4476482)
Affinity DataIC50: 237nMAssay Description:Inhibition of BTK (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase CSK(Human)
University of Silesia In Katowice

Curated by ChEMBL
LigandPNGBDBM50529755(CHEMBL4476482)
Affinity DataIC50: 706nMAssay Description:Inhibition of CSK (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fyn(Human)
University of Silesia In Katowice

Curated by ChEMBL
LigandPNGBDBM50529755(CHEMBL4476482)
Affinity DataIC50: 191nMAssay Description:Inhibition of Fyn A (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
University of Silesia In Katowice

Curated by ChEMBL
LigandPNGBDBM50529755(CHEMBL4476482)
Affinity DataIC50: 515nMAssay Description:Inhibition of LCK (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Silesia In Katowice

Curated by ChEMBL
LigandPNGBDBM50529755(CHEMBL4476482)
Affinity DataIC50: 209nMAssay Description:Inhibition of SRC (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
University of Silesia In Katowice

Curated by ChEMBL
LigandPNGBDBM50529755(CHEMBL4476482)
Affinity DataIC50: 442nMAssay Description:Inhibition of Lyn B (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
University of Silesia In Katowice

Curated by ChEMBL
LigandPNGBDBM50529755(CHEMBL4476482)
Affinity DataIC50: 237nMAssay Description:Inhibition of BTK (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
University of Silesia In Katowice

Curated by ChEMBL
LigandPNGBDBM50529755(CHEMBL4476482)
Affinity DataIC50: 442nMAssay Description:Inhibition of Lyn B (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed