BDBM50529702 CHEMBL4445797

SMILES CC\C=C/C(=O)Nc1cc(Nc2ncc(C#N)c(n2)-c2cn(C)c3ccccc23)c(OC)cc1N(C)CCN(C)C

InChI Key InChIKey=KSQXFPXLNKIUTF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50529702   

TargetEpidermal growth factor receptor(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50529702(CHEMBL4445797)
Affinity DataIC50: 16nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin) using substrate-biotin by ELISA-based mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50529702(CHEMBL4445797)
Affinity DataIC50: 16nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin) using substrate-biotin by ELISA-based mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50529702(CHEMBL4445797)
Affinity DataIC50: 387nMAssay Description:Inhibition of wild-type EGFR (unknown origin) using substrate-biotin by ELISA-based mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50529702(CHEMBL4445797)
Affinity DataIC50: 387nMAssay Description:Inhibition of wild-type EGFR (unknown origin) using substrate-biotin by ELISA-based mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed