BDBM50529693 CHEMBL4451986

SMILES COc1cc(N(C)CCN(C)C)c(NC(=O)\C=C/C)cc1Nc1nccc(n1)-c1cn(C)c2ccccc12

InChI Key InChIKey=JPBAUZVSYQSYPP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50529693   

TargetEpidermal growth factor receptor(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50529693(CHEMBL4451986)
Affinity DataIC50: 52nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin) using substrate-biotin by ELISA-based mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50529693(CHEMBL4451986)
Affinity DataIC50: 395nMAssay Description:Inhibition of wild-type EGFR (unknown origin) using substrate-biotin by ELISA-based mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50529693(CHEMBL4451986)
Affinity DataIC50: 52nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin) using substrate-biotin by ELISA-based mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50529693(CHEMBL4451986)
Affinity DataIC50: 395nMAssay Description:Inhibition of wild-type EGFR (unknown origin) using substrate-biotin by ELISA-based mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed