BDBM50529641 CHEMBL4464640

SMILES COc1ccc(C[C@H](NC(=O)[C@@H](C)NC(=O)C2CCCCC2)C(=O)N[C@@H](Cc2ccccc2)C(=O)[C@@]2(C)CO2)cc1

InChI Key InChIKey=JXHAWXRODIYNNP-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50529641   

TargetProteasome subunit beta type-5(Human)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529641(CHEMBL4464640)
Affinity DataIC50: 185nMAssay Description:Inhibition of 20S proteosome beta 5 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Mouse)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529641(CHEMBL4464640)
Affinity DataIC50: 118nMAssay Description:Inhibition of 20S proteosome beta 5 in mouse A20 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Human)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529641(CHEMBL4464640)
Affinity DataIC50: 29nMAssay Description:Inhibition of LMP7 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Mouse)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529641(CHEMBL4464640)
Affinity DataIC50: 141nMAssay Description:Inhibition of LMP7 in mouse A20 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Mouse)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529641(CHEMBL4464640)
Affinity DataIC50: 118nMAssay Description:Inhibition of 20S proteosome beta 5 in mouse A20 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Mouse)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529641(CHEMBL4464640)
Affinity DataIC50: 141nMAssay Description:Inhibition of LMP7 in mouse A20 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Human)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529641(CHEMBL4464640)
Affinity DataIC50: 29nMAssay Description:Inhibition of LMP7 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529641(CHEMBL4464640)
Affinity DataIC50: 185nMAssay Description:Inhibition of 20S proteosome beta 5 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed