BDBM50529640 CHEMBL4452892

SMILES CC(C)C[C@H](NC(=O)CN1CCCCCC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCc1ccc(C)cc1)C(=O)[C@@]1(C)CO1

InChI Key InChIKey=VQYDMTVFQVMOIH-UHFFFAOYSA-N

Data  24 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 50529640   

TargetProteasome subunit beta type-1(Human)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529640(CHEMBL4452892)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of 20S proteosome beta 1 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Mouse)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529640(CHEMBL4452892)
Affinity DataIC50: 378nMAssay Description:Inhibition of 20S proteosome beta 5 in mouse A20 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-10(Human)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529640(CHEMBL4452892)
Affinity DataIC50: 71nMAssay Description:Inhibition of MECL1 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Human)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529640(CHEMBL4452892)
Affinity DataIC50: 346nMAssay Description:Inhibition of LMP7 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Mouse)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529640(CHEMBL4452892)
Affinity DataIC50: 573nMAssay Description:Inhibition of 20S proteosome beta 2 in mouse A20 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529640(CHEMBL4452892)
Affinity DataIC50: 413nMAssay Description:Inhibition of 20S proteosome beta 2 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-9(Mouse)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529640(CHEMBL4452892)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of LMP2 in mouse A20 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-9(Human)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529640(CHEMBL4452892)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of LMP2 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Mouse)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529640(CHEMBL4452892)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of 20S proteosome beta 1 in mouse A20 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-9(Mouse)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529640(CHEMBL4452892)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of LMP2 in mouse A20 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Mouse)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529640(CHEMBL4452892)
Affinity DataIC50: 378nMAssay Description:Inhibition of 20S proteosome beta 5 in mouse A20 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-10(Human)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529640(CHEMBL4452892)
Affinity DataIC50: 71nMAssay Description:Inhibition of MECL1 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529640(CHEMBL4452892)
Affinity DataIC50: 413nMAssay Description:Inhibition of 20S proteosome beta 2 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-9(Human)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529640(CHEMBL4452892)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of LMP2 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529640(CHEMBL4452892)
Affinity DataIC50: 486nMAssay Description:Inhibition of 20S proteosome beta 5 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Human)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529640(CHEMBL4452892)
Affinity DataIC50: 346nMAssay Description:Inhibition of LMP7 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-10(Mouse)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529640(CHEMBL4452892)
Affinity DataIC50: 305nMAssay Description:Inhibition of MECL1 in mouse A20 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Mouse)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529640(CHEMBL4452892)
Affinity DataIC50: 1.92E+3nMAssay Description:Inhibition of LMP7 in mouse A20 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-10(Mouse)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529640(CHEMBL4452892)
Affinity DataIC50: 305nMAssay Description:Inhibition of MECL1 in mouse A20 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Mouse)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529640(CHEMBL4452892)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of 20S proteosome beta 1 in mouse A20 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Mouse)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529640(CHEMBL4452892)
Affinity DataIC50: 1.92E+3nMAssay Description:Inhibition of LMP7 in mouse A20 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529640(CHEMBL4452892)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of 20S proteosome beta 1 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529640(CHEMBL4452892)
Affinity DataIC50: 486nMAssay Description:Inhibition of 20S proteosome beta 5 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Mouse)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50529640(CHEMBL4452892)
Affinity DataIC50: 573nMAssay Description:Inhibition of 20S proteosome beta 2 in mouse A20 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed