BDBM50529547 CHEMBL4563514

SMILES CS(=O)(=O)c1ccc(N[C@H](c2cccc(Cl)c2)c2ccccn2)c(Nc2ncccn2)c1

InChI Key InChIKey=JZZKDASEJHKEGM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50529547   

TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50529547(CHEMBL4563514)
Affinity DataIC50: 2.28E+4nMAssay Description:Inhibition of 0.5 nM DOT1L (2 to 416 residues) (unknown origin) using biotinylated nucleosome as substrate and [3H]SAM as co-factor preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed