BDBM50529320 CHEMBL4540943

SMILES CCCC[C@H](N)C(=O)NNc1cccc(c1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1

InChI Key InChIKey=HSUTVEOJRBSEAV-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50529320   

TargetEndoplasmic reticulum aminopeptidase 1(Human)
National Centre For Scientific Research "Demokritos

Curated by ChEMBL
LigandPNGBDBM50529320(CHEMBL4540943)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant ERAP1 expressed in baculovirus infected Sf9 cells using omniMMP fluorogenic substrate incubated for 5 to 10 mins by f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor antagonist protein(Human)
National Centre For Scientific Research "Demokritos

Curated by ChEMBL
LigandPNGBDBM50529320(CHEMBL4540943)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of human recombinant IRAP expressed in baculovirus infected Sf9 cells using omniMMP fluorogenic substrate incubated for 5 to 10 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 2(Human)
National Centre For Scientific Research "Demokritos

Curated by ChEMBL
LigandPNGBDBM50529320(CHEMBL4540943)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of human recombinant ERAP2 expressed in baculovirus infected Sf9 cells using omniMMP fluorogenic substrate incubated for 5 to 10 mins by f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor antagonist protein(Human)
National Centre For Scientific Research "Demokritos

Curated by ChEMBL
LigandPNGBDBM50529320(CHEMBL4540943)
Affinity DataKi:  3.80E+3nMAssay Description:Competitive inhibition of human recombinant IRAP expressed in baculovirus infected sf9 cells using L-AMC as substrate incubated for 5 to 10 mins by M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 2(Human)
National Centre For Scientific Research "Demokritos

Curated by ChEMBL
LigandPNGBDBM50529320(CHEMBL4540943)
Affinity DataKi:  4.30E+3nMAssay Description:Competitive inhibition of human recombinant ERAP2 expressed in baculovirus infected sf9 cells using R-AMC as substrate incubated for 5 to 10 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed