BDBM50529311 CHEMBL4472767

SMILES Fc1cccc(c1)-c1cc(F)ccc1OCCN1CCC(CC1)c1c[nH]c2ccc(F)cc12

InChI Key InChIKey=UHDWCHDGCQFNSE-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50529311   

TargetSodium-dependent serotonin transporter(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50529311(CHEMBL4472767)
Affinity DataIC50: 85nMAssay Description:Inhibition of rat synaptosomes 5HT transporter assessed as reduction in [3H]serotonin reuptake incubated for 15 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50529311(CHEMBL4472767)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5HT1A receptor (unknown origin) expressed in HEK293 cells membranes incubated for 60 mins by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50529311(CHEMBL4472767)
Affinity DataKi:  35nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) expressed in CHO cell membranes incubated for 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed