BDBM50529175 CHEMBL4444486

SMILES COc1ccc2[nH]cc(CCNC(=O)c3cc(=O)c4c(OCc5ccc(Br)cc5Br)cccc4o3)c2c1

InChI Key InChIKey=VNQSLBAGTCEQAK-UHFFFAOYSA-N

Data  1 IC50  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50529175   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Univ. Grenoble Alpes

Curated by ChEMBL

LigandBDBM50529175(CHEMBL4444486)Copy SMILESCopy InChI

Affinity DataEC50:  46nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in HEK293 cells assessed as increase in mitoxantrone accumulation incubated for 30 mins by flow cytome...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/25/2021
Entry Details Article
Copy Entry DOIPubMed
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TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Univ. Grenoble Alpes

Curated by ChEMBL

LigandBDBM50529175(CHEMBL4444486)Copy SMILESCopy InChI

Affinity DataIC50: 46nMAssay Description:Inhibition of ABCG2 (unknown origin) by flow cytometryMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/21/2023
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL