BDBM50529148 CHEMBL4582224

SMILES O=C1Sc2ccccc2C2=NCCCN12

InChI Key InChIKey=YDKBMIFGWFISIE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50529148   

TargetHistone deacetylase 4(Human)
University of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50529148(CHEMBL4582224)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of recombinant human N-terminal His6/SUMO-tagged/C-terminal SII-tagged HDAC4 expressed in Escherichia coli BL21 DE3 using Boc-Lys(TFA)-AMC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50529148(CHEMBL4582224)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human full length C-terminal FLAG-tagged HDAC1 expressed in baculovirus infected Sf9 cells using Boc-Lys(Ac)-AMC as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
University of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50529148(CHEMBL4582224)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant human full length N-terminal His6/SUMO-tagged HDAC8 expressed in Escherichia coli BL21 DE3 using Boc-Lys(Ac)-AMC as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50529148(CHEMBL4582224)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 cells using Boc-Lys(Ac)-AMC as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed