BDBM50529134 CHEMBL4516558

SMILES Clc1cccc2SC(=S)N3CCCN=C3c12

InChI Key InChIKey=XOTIQYGBONSIAZ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50529134   

TargetHistone deacetylase 2(Human)
University of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50529134(CHEMBL4516558)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant human full length C-terminal His-tagged HDAC2 expressed in baculovirus infected Sf9 cells using Boc-Lys(Ac)-AMC as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
University of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50529134(CHEMBL4516558)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant human N-terminal His6/SUMO-tagged/C-terminal SII-tagged HDAC4 expressed in Escherichia coli BL21 DE3 using Boc-Lys(TFA)-AMC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
University of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50529134(CHEMBL4516558)
Affinity DataIC50: 130nMAssay Description:Inhibition of recombinant human full length N-terminal His6/SUMO-tagged HDAC8 expressed in Escherichia coli BL21 DE3 using Boc-Lys(Ac)-AMC as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
University of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50529134(CHEMBL4516558)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of recombinant human C-terminal His-tagged HDAC3 (1 to 428 residues) expressed in baculovirus infected Sf9 cells using Boc-Lys(Ac)-AMC as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
University of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50529134(CHEMBL4516558)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged HDAC5 expressed in baculovirus infected Sf9 cells using Boc-Lys(TFA)-AMC as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50529134(CHEMBL4516558)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of recombinant human full length C-terminal FLAG-tagged HDAC1 expressed in baculovirus infected Sf9 cells using Boc-Lys(Ac)-AMC as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50529134(CHEMBL4516558)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 cells using Boc-Lys(Ac)-AMC as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed