BDBM50528956 CHEMBL4449452

SMILES CN(C(=O)c1ccc(Cc2c[nH]c3nc(N)[nH]c(=O)c23)cc1)c1ccccc1C(O)=O

InChI Key InChIKey=PVBGMRZWGXVLEL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50528956   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium parvum)
Yale University

Curated by ChEMBL
LigandPNGBDBM50528956(CHEMBL4449452)
Affinity DataIC50: 2.10E+5nMAssay Description:Inhibition of recombinant Cryptosporidium hominis TS-DHFR expresssed in Escherichia coli PA414 using dUMP and 5,10-methylenetetrahydrofolate as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed