BDBM50528843 CHEMBL4516736

SMILES Clc1ccc(cc1)C1CC(=NN1c1nc(cs1)-c1ccc(cc1)C#N)c1ccc(cc1)N1CCOCC1

InChI Key InChIKey=MFRSLBCAYUHKEI-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50528843   

TargetInsulin receptor(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50528843(CHEMBL4516736)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged INSR (1011 to end residues) expressed in baculovirus infected Sf9 insect cells using Axltide as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50528843(CHEMBL4516736)
Affinity DataIC50: 2.28E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged HER2 (676 to end residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50528843(CHEMBL4516736)
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged KDR (789 to end residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 Gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50528843(CHEMBL4516736)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged PDGFRalpha (550 to end residues) expressed in baculovirus infected Sf9 insect cells using Poly ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50528843(CHEMBL4516736)
Affinity DataIC50: 4.34E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR (695 to end residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50528843(CHEMBL4516736)
Affinity DataIC50: 4.68E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged HER4 (682 to 993 residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50528843(CHEMBL4516736)
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged IGF1R (960 to end residues) expressed in baculovirus infected Sf9 insect cells using IGF1Rtide ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50528843(CHEMBL4516736)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged PDGFRbeta (557 to end residues) expressed in baculovirus infected Sf9 insect cells using Poly (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed