BDBM50528809 CHEMBL4589249

SMILES COc1cc(F)ccc1-c1cc(Nc2cc(C[S@](C)(=N)=O)ccn2)ncc1F

InChI Key InChIKey=YZCUMZWULWOUMD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50528809   

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50528809(CHEMBL4589249)
Affinity DataIC50: 3nMAssay Description:Competitive reversible inhibition of recombinant full-length His-tagged human CDK9/cyclin T expressed in baculovirus infected insect cells using biot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50528809(CHEMBL4589249)
Affinity DataIC50: 4nMAssay Description:Competitive reversible inhibition of recombinant full-length His-tagged human CDK9/cyclin T expressed in baculovirus infected insect cells using biot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50528809(CHEMBL4589249)
Affinity DataIC50: 6nMAssay Description:Inhibition of CDK9 (unknown origin) in high presence of high ATP incubated for 25 min by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed