BDBM50528653 CHEMBL4586740

SMILES Oc1c(CNCCCC(=O)Nc2ccccc2)cc(Cl)c2cccnc12

InChI Key InChIKey=GPYUMRKOXLEEOM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50528653   

Target72 kDa type IV collagenase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50528653(CHEMBL4586740)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of recombinant human MMP2 using thiopeptide as substrate preincubated for 30 mins followed by substrate addition and measured every mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50528653(CHEMBL4586740)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of recombinant human MMP9 using thiopeptide as substrate preincubated for 30 mins followed by substrate addition and measured every min fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed