BDBM50528592 CHEMBL4458458

SMILES COc1cc(OC)cc(c1)C(P(O)(O)=O)S(=O)(=O)CC(=O)N(C)O

InChI Key InChIKey=XELRRDNEFKKXKL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50528592   

Target1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic(Plasmodium falciparum (isolate 3D7))
Heinrich Heine University D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50528592(CHEMBL4458458)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of recombinant Plasmodium falciparum IspC expressed in Escherichia coli using 1-deoxy-D-xylulose 5-phosphate as substrate by photometric a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
Heinrich Heine University D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50528592(CHEMBL4458458)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of recombinant Escherichia coli IspC expressed in Escherichia coli M15 using 1-deoxy-D-xylulose 5-phosphate as substrate by photometric as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Heinrich Heine University D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50528592(CHEMBL4458458)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis IspC expressed in Escherichia coli M15 using 1-deoxy-D-xylulose 5-phosphate as substrate by phot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed