BDBM50527028 CHEMBL4441366

SMILES CC(=O)NCCN(Cc1ccccn1)C(=O)c1nn(C)c-2c1COc1ccc(Br)cc-21

InChI Key InChIKey=GFRDPGNGZLQWAR-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50527028   

TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527028(CHEMBL4441366)
Affinity DataEC50:  2.17E+3nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527028(CHEMBL4441366)
Affinity DataEC50:  4.80E+3nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed