BDBM50526884 CHEMBL4454874

SMILES CC(C)c1ccc2nc(NC(=O)c3ccc(cc3)N3CCOCC3)sc2c1

InChI Key InChIKey=HPIYMKMTJVEICQ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50526884   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Csic

Curated by ChEMBL

LigandBDBM50526884(CHEMBL4454874)Copy SMILESCopy InChI

Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of wild type human GST-tagged LRRK2 (970 to 2527 residues) expressed in baculovirus expression system assessed as reduction in ADP formati...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/25/2021
Entry Details Article
Copy Entry DOIPubMed
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TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Csic

Curated by ChEMBL

LigandBDBM50526884(CHEMBL4454874)Copy SMILESCopy InChI

Affinity DataIC50: 980nMAssay Description:Inhibition of human GST-tagged LRRK2 G2019S mutant (970 to 2527 residues) expressed in baculovirus expression system assessed as reduction in ADP for...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/25/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL