BDBM50526875 CHEMBL4466297

SMILES CNC(=O)c1cc(Oc2cccc3nc(NC(=O)Nc4ccc(Cl)c(c4)C(F)(F)F)ccc23)ccn1

InChI Key InChIKey=KXQLSPVERYRNCS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50526875   

TargetSerine/threonine-protein kinase B-raf(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50526875(CHEMBL4466297)
Affinity DataIC50: 316nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50526875(CHEMBL4466297)
Affinity DataIC50: 61nMAssay Description:Inhibition of c-RAF (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed