BDBM50526846 CHEMBL4559629

SMILES Brc1ccc(Cn2c(CC3CC4CCC3C4)nc3ccccc23)cc1

InChI Key InChIKey=YZRWDZKZHROWMN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50526846   

TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50526846(CHEMBL4559629)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 2(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50526846(CHEMBL4559629)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of HO-2 in Sprague-Dawley rat brain microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50526846(CHEMBL4559629)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsome HO-1 preincubated for 10 mins followed by beta-NADPH addition and measured after 15 mins by gas chr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHeme oxygenase 2(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50526846(CHEMBL4559629)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of Sprague-Dawley rat brain microsome HO-2 preincubated for 10 mins followed by beta-NADPH addition and measured after 15 mins by gas chro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed