BDBM50526810 CHEMBL4443505

SMILES COc1ccc(C[C@H](NC(=O)[C@H](C)NC(=O)CN2CCOCC2)C(=O)N[C@@H](CC2=CCCC2)C(=O)[C@@]2(C)CO2)cc1

InChI Key InChIKey=CLZRGXQPCQFFTL-UHFFFAOYSA-N

Data  22 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 22 hits for monomerid = 50526810   

TargetProteasome subunit beta type-9(Human)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50526810(CHEMBL4443505)
Affinity DataIC50: 223nMAssay Description:Inhibition of LMP2 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Hangzhou Xixi Hospital

Curated by ChEMBL
LigandPNGBDBM50526810(CHEMBL4443505)
Affinity DataIC50: 3.64E+4nMAssay Description:Inhibition of 20S proteasome beta 1c (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Hangzhou Xixi Hospital

Curated by ChEMBL
LigandPNGBDBM50526810(CHEMBL4443505)
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of 20S proteasome beta 2c (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-10(Human)
Hangzhou Xixi Hospital

Curated by ChEMBL
LigandPNGBDBM50526810(CHEMBL4443505)
Affinity DataIC50: 1.44E+3nMAssay Description:Inhibition of 20S proteasome beta 2i (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Hangzhou Xixi Hospital

Curated by ChEMBL
LigandPNGBDBM50526810(CHEMBL4443505)
Affinity DataIC50: 926nMAssay Description:Inhibition of 20S proteasome beta 5c (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Human)
Hangzhou Xixi Hospital

Curated by ChEMBL
LigandPNGBDBM50526810(CHEMBL4443505)
Affinity DataIC50: 83nMAssay Description:Inhibition of 20S proteasome beta 5i (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-9(Human)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50526810(CHEMBL4443505)
Affinity DataIC50: 223nMAssay Description:Inhibition of 20S proteasome beta 1i (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Mouse)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50526810(CHEMBL4443505)
Affinity DataIC50: 694nMAssay Description:Inhibition of 20S proteosome beta 5 in mouse A20 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Hangzhou Xixi Hospital

Curated by ChEMBL
LigandPNGBDBM50526810(CHEMBL4443505)
Affinity DataIC50: 3.64E+4nMAssay Description:Inhibition of 20S proteosome beta 1 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Hangzhou Xixi Hospital

Curated by ChEMBL
LigandPNGBDBM50526810(CHEMBL4443505)
Affinity DataIC50: 926nMAssay Description:Inhibition of 20S proteosome beta 5 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Mouse)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50526810(CHEMBL4443505)
Affinity DataIC50: 110nMAssay Description:Inhibition of LMP7 in mouse A20 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-10(Human)
Hangzhou Xixi Hospital

Curated by ChEMBL
LigandPNGBDBM50526810(CHEMBL4443505)
Affinity DataIC50: 1.44E+3nMAssay Description:Inhibition of MECL1 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Mouse)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50526810(CHEMBL4443505)
Affinity DataIC50: 110nMAssay Description:Inhibition of LMP7 in mouse A20 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Hangzhou Xixi Hospital

Curated by ChEMBL
LigandPNGBDBM50526810(CHEMBL4443505)
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of 20S proteosome beta 2 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-10(Human)
Hangzhou Xixi Hospital

Curated by ChEMBL
LigandPNGBDBM50526810(CHEMBL4443505)
Affinity DataIC50: 1.44E+3nMAssay Description:Inhibition of MECL1 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-9(Human)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50526810(CHEMBL4443505)
Affinity DataIC50: 223nMAssay Description:Inhibition of LMP2 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Human)
Hangzhou Xixi Hospital

Curated by ChEMBL
LigandPNGBDBM50526810(CHEMBL4443505)
Affinity DataIC50: 83nMAssay Description:Inhibition of LMP7 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Mouse)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50526810(CHEMBL4443505)
Affinity DataIC50: 694nMAssay Description:Inhibition of 20S proteosome beta 5 in mouse A20 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Hangzhou Xixi Hospital

Curated by ChEMBL
LigandPNGBDBM50526810(CHEMBL4443505)
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of 20S proteosome beta 2 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Hangzhou Xixi Hospital

Curated by ChEMBL
LigandPNGBDBM50526810(CHEMBL4443505)
Affinity DataIC50: 3.64E+4nMAssay Description:Inhibition of 20S proteosome beta 1 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Hangzhou Xixi Hospital

Curated by ChEMBL
LigandPNGBDBM50526810(CHEMBL4443505)
Affinity DataIC50: 926nMAssay Description:Inhibition of 20S proteosome beta 5 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Human)
Hangzhou Xixi Hospital

Curated by ChEMBL
LigandPNGBDBM50526810(CHEMBL4443505)
Affinity DataIC50: 83nMAssay Description:Inhibition of LMP7 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed