BDBM50526722 CHEMBL4457897

SMILES Cn1cc(cn1)-c1cc(cc(c1)S(=O)(=O)c1cnc(CN)s1)S(C)(=O)=O

InChI Key InChIKey=AFJUDDQTSKTAGP-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50526722   

TargetAmine oxidase [copper-containing] 3(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50526722(CHEMBL4457897)
Affinity DataIC50: 1.33E+4nMAssay Description:Inhibition of recombinant human SSAO expressed in CHO cells using luminogenic MAO substrate measured after 1 hr by MAO-glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLysyl oxidase homolog 3(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50526722(CHEMBL4457897)
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of recombinant C-terminal His-tagged human LOXL3 (1 to 753 residues) expressed in CHO cells using cadaverine hydrochloride as substrate pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50526722(CHEMBL4457897)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human MAOB expressed in baculovirus infected BTI insect cells using luminogenic MAO substrate measured after 1 hr by MAO-gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Pig)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50526722(CHEMBL4457897)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of porcine kidney DAO measured after 1 hrs by ROS-glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50526722(CHEMBL4457897)
Affinity DataIC50: 109nMAssay Description:Inhibition of human C-terminal His10-tagged LOXL2 (Met1 to Gln774 residues) expressed in mouse NS0 cells using cadaverine hydrochloride as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50526722(CHEMBL4457897)
Affinity DataIC50: 69nMAssay Description:Inhibition of human C-terminal His10-tagged LOXL2 (Met1 to Gln774 residues) expressed in mouse NS0 cells using cadaverine hydrochloride as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50526722(CHEMBL4457897)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human MAOA expressed in baculovirus infected BTI insect cells using luminogenic MAO substrate measured after 1 hr by MAO-gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50526722(CHEMBL4457897)
Affinity DataIC50: 331nMAssay Description:Inhibition of human C-terminal His10-tagged LOXL2 (Met1 to Gln774 residues) expressed in mouse NS0 cells using cadaverine hydrochloride as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed