BDBM50526702 CHEMBL4463974

SMILES Cn1nccc1-c1ccc(Sc2ccc(cc2)C2(CCOCC2)C(N)=O)cc1

InChI Key InChIKey=FOZCXBPUVVQDLR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50526702   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
School of Advanced Sciences

Curated by ChEMBL
LigandPNGBDBM50526702(CHEMBL4463974)
Affinity DataIC50: 229nMAssay Description:Inhibition of recombinant human 5-LOX expressed in baculovirus-infected insect cells preincubated for 10 mins followed by Arachidonic acid and ATP ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50526702(CHEMBL4463974)
Affinity DataIC50: 229nMAssay Description:Inhibition of guinea pig leukotriene D4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
School of Advanced Sciences

Curated by ChEMBL
LigandPNGBDBM50526702(CHEMBL4463974)
Affinity DataIC50: 229nMAssay Description:Inhibition of recombinant 5-LOX (unknown origin) using H2DCFDA as substrate by measuring fluorescent 2',7'-dichlorofluorescein incubated for 35 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed