BDBM50526390 CHEMBL4462401

SMILES OC1(CC1)C(=O)N1CCN(CC1)C(=O)c1ccc(cc1)-c1ccc2scnc2c1

InChI Key InChIKey=BPBUDVIJYFCWSO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50526390   

TargetFatty acid synthase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50526390(CHEMBL4462401)
Affinity DataIC50: 32nMAssay Description:Inhibition of full length recombinant human FASN using acetyl-CoA/malonyl-CoA as substrate preincubated for 60 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50526390(CHEMBL4462401)
Affinity DataIC50: 11nMAssay Description:Inhibition of FASN in human BT474 cells preincubated for 1 hr followed by [14C]-acetate addition and measured after 4 hrs by scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed