BDBM50525953 CHEMBL4437589

SMILES CN1CCN(CC1)C2=Nc3c(cccc3F)C(=O)N2c4ccc(cc4)Oc5ccc(cc5)F

InChI Key InChIKey=NUGPMKZYSBKNPU-UHFFFAOYSA-N

Data  1 EC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50525953   

TargetTransient receptor potential cation channel subfamily V member 4(Human)
Asahi Kasei Medical

Curated by ChEMBL

LigandBDBM50525953(CHEMBL4437589)Copy SMILESCopy InChI

Affinity DataEC50:  60nMAssay Description:Agonist activity at recombinant human TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium level after 30 mins by Fura-2 AM/...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidPDBSimilars

In Depth
Date in BDB:
2/25/2021
Entry Details Article
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