BDBM50525879 CHEMBL4541404

SMILES O=C(CNC(=O)C(C#N)c1nc2ccc(cc2s1)-c1ccc2C(=O)NCc2c1)NC1CC1

InChI Key InChIKey=PPOFQLCKXICRRP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50525879   

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50525879(CHEMBL4541404)
Affinity DataIC50: 70nMAssay Description:Inhibition of hepatic lipase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetEndothelial lipase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50525879(CHEMBL4541404)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of endothelial lipase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetEndothelial lipase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50525879(CHEMBL4541404)
Affinity DataIC50: 100nMAssay Description:Inhibition of endothelial lipase in human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed