BDBM50525870 CHEMBL4459874

SMILES Fc1ccc(cn1)-c1ccc2nc(sc2c1)C(C#N)C(=O)NCC(=O)NC1CC1

InChI Key InChIKey=VJULUWPPORLTHQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50525870   

TargetEndothelial lipase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50525870(CHEMBL4459874)
Affinity DataIC50: 230nMAssay Description:Inhibition of endothelial lipase in human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetEndothelial lipase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50525870(CHEMBL4459874)
Affinity DataIC50: 170nMAssay Description:Inhibition of endothelial lipase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50525870(CHEMBL4459874)
Affinity DataIC50: 500nMAssay Description:Inhibition of hepatic lipase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed