BDBM50525714 CHEMBL4535656

SMILES OCc1ccc(cc1)C(=O)OCC(=O)Nc1cccc(c1)C(F)(F)F

InChI Key InChIKey=SFWLMMSHFJHLQJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50525714   

TargetBDNF/NT-3 growth factors receptor(Human)
Zoetis

Curated by ChEMBL
LigandPNGBDBM50525714(CHEMBL4535656)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant full length human TrkB transfected in CHO cells assessed as inhibition of NGF-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
LigandPNGBDBM50525714(CHEMBL4535656)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of recombinant full length human TrkA transfected in CHO cells assessed as inhibition of NGF-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
LigandPNGBDBM50525714(CHEMBL4535656)
Affinity DataIC50: 144nMAssay Description:Inhibition of recombinant human His-tagged TrkA kinase domain (441-796 residues) expressed in baculovirus expression system incubated with enzyme/ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed