BDBM50525617 CHEMBL4560388

SMILES Cc1c(Cl)cccc1OCc1cc(=O)n2nc(nc2[nH]1)-c1ccccc1

InChI Key InChIKey=DHVPJCVPOZYDTH-UHFFFAOYSA-N

Data  5 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50525617   

TargetFatty acid-binding protein, adipocyte(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50525617(CHEMBL4560388)
Affinity DataIC50: 6.34E+3nMAssay Description:Displacement of 1,8-ANS from human recombinant full length N-terminal his-tagged FABP4 expressed in Escherichia coli BL21 (DE3) incubated for 3 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetFatty acid-binding protein 5(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50525617(CHEMBL4560388)
Affinity DataIC50: 2.34E+4nMAssay Description:Displacement of 1,8-ANS from human recombinant full length N-terminal his-tagged FABP5 expressed in Escherichia coli BL21 (DE3) incubated for 3 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetFatty acid-binding protein, heart(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50525617(CHEMBL4560388)
Affinity DataIC50: 1.95E+3nMAssay Description:Displacement of 1,8-ANS from FABP3 (unknown origin) incubated for 3 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetFatty acid-binding protein, heart(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50525617(CHEMBL4560388)
Affinity DataKd:  520nMAssay Description:Binding affinity to human FABP3 expressed in Escherichia coli assessed as degree of fluorescent shift by temperature-dependent fluorescence thermal s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFatty acid-binding protein, adipocyte(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50525617(CHEMBL4560388)
Affinity DataKd:  10nMAssay Description:Binding affinity to human FABP4 expressed in Escherichia coli assessed as degree of fluorescent shift by temperature-dependent fluorescence thermal s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFatty acid-binding protein, heart(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50525617(CHEMBL4560388)
Affinity DataIC50: 800nMAssay Description:Displacement of BODIPY 500/510 C4 from human FABP3 expressed in Escherichia coli incubated for 30 mins by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFatty acid-binding protein, adipocyte(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50525617(CHEMBL4560388)
Affinity DataIC50: 1.40E+3nMAssay Description:Displacement of BODIPY 500/510 C4 from human FABP4 expressed in Escherichia coli incubated for 30 mins by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed