BDBM50525583 CHEMBL4461649

SMILES NCC1(COC1)c1cccc(c1)-c1ccnc2[nH]nc(c12)C(F)(F)F

InChI Key InChIKey=WQSBBBAQXNAUEM-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50525583   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50525583(CHEMBL4461649)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50525583(CHEMBL4461649)
Affinity DataKi:  6nMAssay Description:Inhibition of human recombinant full length His tagged PKC theta expressed in baculovirus using ERMRPRKRQGSVRRRV peptide as substrate incubated for 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50525583(CHEMBL4461649)
Affinity DataKi:  392nMAssay Description:Inhibition of recombinant full length PKC delta (unknown origin) using ERMRPRKR- QGSVRRRV peptide as substrate measured after 15 mins in presence of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50525583(CHEMBL4461649)
Affinity DataKi:  1.02E+3nMAssay Description:Inhibition of recombinant full length PKC alpha (unknown origin) using RRRRRKGSFKRKA peptide as substrate measured after 15 mins in presence of ATP b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50525583(CHEMBL4461649)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of human PKC betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed