BDBM50525513 CHEMBL4558790

SMILES OC(=O)c1ccc(Nc2ccnc(SCC(=O)c3ccc(cc3)C#N)n2)cc1

InChI Key InChIKey=MRTAWDRTQCYMNF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50525513   

TargetVascular endothelial growth factor receptor 2(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50525513(CHEMBL4558790)
Affinity DataIC50: 120nMAssay Description:Inhibition of human N-terminal GST tagged VEGFR-2 expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4:1 as substrate in presence of AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50525513(CHEMBL4558790)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human wild type BRAF by Kinase-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed