BDBM50525250 CHEMBL4526128

SMILES c1ccc(cc1)C2=CC(=C3N(C2=O)c4cc(ccc4S3)OC5CCCCC5)C(=O)N[C@@H](Cc6ccc(cc6)O)C(=O)O

InChI Key InChIKey=PTUWWNGMUPSKDC-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50525250   

TargetGenome polyprotein(Dengue virus)
Queensland University of Technology

Curated by ChEMBL
LigandPNGBDBM50525250(CHEMBL4526128)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of N-terminal His6-tagged DENV3 NS5 RNA dependent RNA polymerase (272 to 900 residues) after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50525250(CHEMBL4526128)
Affinity DataIC50: 2.76E+4nMAssay Description:Inhibition of SARS-CoV-2 RdRp incubated for 60 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50525250(CHEMBL4526128)
Affinity DataIC50: 9.61E+3nMAssay Description:Inhibition of DENV-2 DENV2 NS2B-NS3More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed