BDBM50525190 CHEMBL4442696

SMILES [H][C@]1(CSC(N)=N1)[C@@H](C)C(O)=O

InChI Key InChIKey=HQCCRLRYTXVTRA-UHFFFAOYSA-N

Data  4 IC50  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50525190   

TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50525190(CHEMBL4442696)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at recombinant human GABA-A rho-1 receptor transiently expressed in human tsA201 cells incubated for 30 mins and measured up to 90 s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50525190(CHEMBL4442696)
Affinity DataEC50:  3.00E+3nMAssay Description:Agonist activity at recombinant human GABA-A alpha5beta2gamma2S receptor transiently expressed in human tsA201 cells incubated for 30 mins and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 3(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50525190(CHEMBL4442696)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human GAT3 expressed in Flp-In CHO cells assessed as reduction in [3H]GABA uptake incubated for 3 mins by liquid scintillation counting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50525190(CHEMBL4442696)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human BGT1 expressed in Flp-In CHO cells assessed as reduction in [3H]GABA uptake incubated for 3 mins by liquid scintillation counting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50525190(CHEMBL4442696)
Affinity DataEC50:  9.77E+3nMAssay Description:Agonist activity at recombinant human GABA-A alpha1beta2gamma2S receptor transiently expressed in human tsA201 cells incubated for 30 mins and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50525190(CHEMBL4442696)
Affinity DataEC50:  3.02E+3nMAssay Description:Agonist activity at recombinant human GABA-A alpha5beta2gamma2S receptor transiently expressed in human tsA201 cells incubated for 30 mins and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50525190(CHEMBL4442696)
Affinity DataEC50:  1.59E+3nMAssay Description:Agonist activity at recombinant human GABA-A rho-1 receptor transiently expressed in human tsA201 cells incubated for 30 mins and measured up to 90 s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50525190(CHEMBL4442696)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human GAT1 expressed in Flp-In CHO cells assessed as reduction in [3H]GABA uptake incubated for 3 mins by liquid scintillation counting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50525190(CHEMBL4442696)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human GAT2 expressed in Flp-In CHO cells assessed as reduction in [3H]GABA uptake incubated for 3 mins by liquid scintillation counting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50525190(CHEMBL4442696)
Affinity DataEC50:  9.70E+3nMAssay Description:Agonist activity at recombinant human GABA-A alpha1beta2gamma2S receptor transiently expressed in human tsA201 cells incubated for 30 mins and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed