BDBM50525139 CHEMBL4554682

SMILES C[C@H](NC(=O)[C@H](CCCCN)NC(C)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCCN1CCN(CCCCC2CCN(CC(=O)N3c4ccccc4NC(=O)c4ccccc34)CC2)CC1

InChI Key InChIKey=AKPOTJIMZXGFLY-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50525139   

TargetMuscarinic acetylcholine receptor M2(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50525139(CHEMBL4554682)
Affinity DataKi:  0.174nMAssay Description:Displacement of [3H]-NMS from human muscarinic M2 receptor expressed in CHO-K9 cells after 3 hrs by microbeta2 scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50525139(CHEMBL4554682)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]-NMS from human muscarinic M1 receptor expressed in CHO-K9 cells after 3 hrs by microbeta2 scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50525139(CHEMBL4554682)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]-NMS from human muscarinic M4 receptor expressed in CHO-K9 cells after 3 hrs by microbeta2 scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50525139(CHEMBL4554682)
Affinity DataKi:  45nMAssay Description:Displacement of [3H]-NMS from human muscarinic M3 receptor expressed in CHO-K9 cells after 3 hrs by microbeta2 scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50525139(CHEMBL4554682)
Affinity DataKi:  95nMAssay Description:Displacement of [3H]-NMS from human muscarinic M5 receptor expressed in CHO-K9 cells after 3 hrs by microbeta2 scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed