BDBM50524882 CHEMBL4465202

SMILES Cc1cc(OCCCC(=O)Nc2ncc(Br)s2)ccc1Cl

InChI Key InChIKey=LPJBTTAJGCQDJA-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50524882   

TargetProtein Tat(HIV-1)
The Walter and Eliza Hall Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50524882(CHEMBL4465202)
Affinity DataEC50:  3.60E+3nMAssay Description:Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProtein Tat(HIV-1)
The Walter and Eliza Hall Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50524882(CHEMBL4465202)
Affinity DataEC50: >4.00E+4nMAssay Description:Activation of Tat-mediated HIV1 transcription in J-Lat 10.6 cells harboring LTR driven GFP reporter co-expressing CMV driven RFP reporter assessed as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SETD1B(Human)
The Walter and Eliza Hall Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50524882(CHEMBL4465202)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of C-terminal GST-tagged human SET1B (1629 to 1923 amino acids) expressed in Escherichia coli using core histone as substrate in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed