BDBM50524878 CHEMBL4583543
SMILES Cc1cnc(NC(=O)CCCOc2ccccc2)s1
InChI Key InChIKey=MWHQQWNHUURCGY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50524878
Affinity DataEC50: 2.90E+4nMAssay Description:Activation of Tat-mediated HIV1 transcription in HEK293-FlpIn.RV cells harboring LTR driven CBG reporter co-expressing CMV driven CBR reporter assess...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Human)
The Walter and Eliza Hall Institute For Medical Research
Curated by ChEMBL
The Walter and Eliza Hall Institute For Medical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of His-tagged BRD4 bromodomain 1 (unknown origin) using H4 peptide as substrate pre-incubated for 30 mins followed by substrate addition a...More data for this Ligand-Target Pair
Affinity DataEC50: 2.40E+4nMAssay Description:Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...More data for this Ligand-Target Pair
Affinity DataEC50: >4.00E+4nMAssay Description:Activation of Tat-mediated HIV1 transcription in J-Lat 10.6 cells harboring LTR driven GFP reporter co-expressing CMV driven RFP reporter assessed as...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Human)
The Walter and Eliza Hall Institute For Medical Research
Curated by ChEMBL
The Walter and Eliza Hall Institute For Medical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of His-tagged BRD4 bromodomain 2 (unknown origin) using H4 peptide as substrate pre-incubated for 30 mins followed by substrate addition a...More data for this Ligand-Target Pair