BDBM50524830 CHEMBL4568168

SMILES COc1ccc(\C=C\C(=O)c2cc(OC)c(OC)c(OC)c2)cc1OCCCCCCC(=O)NO

InChI Key InChIKey=PTVNFJFTCMFJGK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50524830   

TargetHistone deacetylase(Human)
Qingdao University

Curated by ChEMBL
LigandPNGBDBM50524830(CHEMBL4568168)
Affinity DataIC50: 133nMAssay Description:Inhibition of HDAC in human HeLA cell nuclear extractsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Qingdao University

Curated by ChEMBL
LigandPNGBDBM50524830(CHEMBL4568168)
Affinity DataIC50: 36nMAssay Description:Inhibition of HDAC1 (unknown origin) using Boc-Lys(Ac)-AMC as substrate incubated for 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Qingdao University

Curated by ChEMBL
LigandPNGBDBM50524830(CHEMBL4568168)
Affinity DataIC50: 3.88E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(Ac)-AMC as substrate incubated for 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Qingdao University

Curated by ChEMBL
LigandPNGBDBM50524830(CHEMBL4568168)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of HDAC6 (unknown origin) using Boc-Lys(Ac)-AMC as substrate incubated for 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed