BDBM50524817 CHEMBL4583962

SMILES CC(C)C(NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)(C)C)P(=O)(Oc1ccccc1)Oc1ccccc1

InChI Key InChIKey=KAOFRGOIKKCOFS-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50524817   

TargetNeutrophil elastase(Human)
University of Otago

Curated by ChEMBL
LigandPNGBDBM50524817(CHEMBL4583962)
Affinity DataIC50: 680nMAssay Description:Inhibition of human neutrophil elastase using AAPV-pNA as substrate preincubated for 15 mins followed by substrate addition and measured every 15 sec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetTrypsin(Human)
University of Otago

Curated by ChEMBL
LigandPNGBDBM50524817(CHEMBL4583962)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of human trypsin using Nalpha-benzoyl-DL-R-pNA as substrate preincubated for 15 mins followed by substrate addition and measured every 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProbable periplasmic serine endoprotease DegP-like(Chlamydia trachomatis (strain D/UW-3/Cx))
University of Otago

Curated by ChEMBL
LigandPNGBDBM50524817(CHEMBL4583962)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of recombinant ctHtrA serine protease using MeOCoum-ENLHLPLPI1F-D as substrate pretreated for 10 min followed by substrate addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
University of Otago

Curated by ChEMBL
LigandPNGBDBM50524817(CHEMBL4583962)
Affinity DataIC50: 3.02E+3nMAssay Description:Inhibition of human neutrophil elastase using methoxysuccinyl-Ala-Ala-Pro-Val-pNA as substrate incubated for 15 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetProbable periplasmic serine endoprotease DegP-like(Chlamydia trachomatis (strain D/UW-3/Cx))
University of Otago

Curated by ChEMBL
LigandPNGBDBM50524817(CHEMBL4583962)
Affinity DataIC50: 1.59E+4nMAssay Description:Inhibition of recombinant Chlamydia trachomatis HtrA serine protease using MeOCoum-ENLHLPLPI1F-D as substrate measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetNeutrophil elastase(Human)
University of Otago

Curated by ChEMBL
LigandPNGBDBM50524817(CHEMBL4583962)
Affinity DataIC50: 3.02E+3nMAssay Description:Inhibition of human neutrophil elastase using methoxysuccinyl-Ala-Ala-Pro-Val-pNA as substrate incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed