BDBM50524592 CHEMBL4550944

SMILES OC(C1COC(=O)C1=C)c1cn(Cc2ccc(F)cc2)c2ccc(Cl)cc12

InChI Key InChIKey=IVUDIWYRPBANNV-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50524592   

TargetLysine-specific histone demethylase 1A(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50524592(CHEMBL4550944)
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of recombinant LSD1 (unknown origin) (catalytic domain 157 to 852 residues) expressed in Escherichia coli BL21 using H3K4me1 as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50524592(CHEMBL4550944)
Affinity DataKd:  2.02E+5nMAssay Description:Binding affinity to LSD1 (unknown origin) assessed as dissociation constant by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed