BDBM50524399 CHEMBL4462572

SMILES CCOC(=O)c1[nH]c2cc(Cl)ccc2c1\C=N\NC(=O)c1cc(nn1Cc1cccc(C)c1)C(C)(C)C

InChI Key InChIKey=DFFPGPQFYXXQPX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50524399   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50524399(CHEMBL4462572)
Affinity DataIC50: 4.22E+3nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged 15-LOX1 expressed in Escherichia coli BL21(DE3) using linoleic acid as substrate preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed