BDBM50524273 CHEMBL4447840

SMILES CCCCCCC(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(CO)CO1

InChI Key InChIKey=HPAGFWZVTGGUPS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50524273   

TargetProteasome subunit beta type-9(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50524273(CHEMBL4447840)
Affinity DataIC50: 36nMAssay Description:Inhibition of purified human 20S immunoproteasome beta1 subunit using Ac-Pro-Ala-Leu-AMC as substrate pretreated for 1 hr followed by substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50524273(CHEMBL4447840)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of 20S proteasome beta5 subunit in human RPMI8226 cell lysate using Suc-LLVY-AMC as substrate pretreated for 1 hr followed by substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed