BDBM50524242 CHEMBL4441703::US12297164, Example 7

SMILES CCCCC(=O)Nc1ccc(cc1)-c1ccc(cc1F)C(O)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=SUFZTAQHSUQWTN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50524242   

TargetNuclear receptor ROR-gamma(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50524242(CHEMBL4441703 | US12297164, Example 7)
Affinity DataIC50: 4.17E+3nMAssay Description:Inverse agonist activity at Gal4-fused RORgamma LBD (unknown origin) expressed in 293T cells measured after 24 hrs by dual-luciferase reporter gene a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50524242(CHEMBL4441703 | US12297164, Example 7)
Affinity DataIC50: 1.02E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2025
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50524242(CHEMBL4441703 | US12297164, Example 7)
Affinity DataIC50: 4.17E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2025
Entry Details
Go to US Patent