BDBM50524178 CHEMBL4470299

SMILES Cc1ccc(NCc2ccnn2-c2nnc(s2)N2CCC(CC2)C(=O)Nc2cnccc2C)nc1

InChI Key InChIKey=KBUHQQYSJQKOBA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50524178   

TargetSmoothened homolog(Mouse)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50524178(CHEMBL4470299)
Affinity DataIC50: 550nMAssay Description:Antagonist activity at Smo receptor in mouse NIH/3T3 cells harboring GRE-Luc assessed as inhibition of SAG-induced Hh signaling pathway preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed