BDBM50524173 CHEMBL4588930

SMILES Cc1ccc(NCc2ccnn2-c2nnc(s2)N2CCC(CC2)C(=O)Nc2ccccc2C)nc1

InChI Key InChIKey=VFUWNEXBWKSDNZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50524173   

TargetSmoothened homolog(Mouse)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50524173(CHEMBL4588930)
Affinity DataIC50: 140nMAssay Description:Antagonist activity at Smo receptor in mouse NIH/3T3 cells harboring GRE-Luc assessed as inhibition of SAG-induced Hh signaling pathway preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50524173(CHEMBL4588930)
Affinity DataIC50: 141nMAssay Description:Antagonist activity at Smo receptor in mouse NIH/3T3 cells harboring GRE-Luc assessed as inhibition of SAG-induced Hh signaling pathway preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed