BDBM50524142 CHEMBL4443644

SMILES NS(=O)(=O)c1ccc(cc1)-n1ncc(C#N)c1NC(=O)CCN1CCOCC1

InChI Key InChIKey=WDCSJGAJZYETNP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50524142   

TargetProstaglandin G/H synthase 2(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50524142(CHEMBL4443644)
Affinity DataIC50: 39nMAssay Description:Inhibition of human recombinant COX-2 assessed as reduction in PGF2alpha formation using arachidonic acid as substrate preincubated with enzyme for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50524142(CHEMBL4443644)
Affinity DataIC50: 876nMAssay Description:Inhibition of human recombinant COX1 assessed as reduction in PGF2alpha formation using arachidonic acid as substrate preincubated with enzyme for 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed