BDBM50524096 CHEMBL4455565

SMILES COc1cc2N=C(NC(=O)c3cccnc3)N3CCN=C3c2cc1OC

InChI Key InChIKey=UFZHZUCJLDSWSY-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50524096   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
University Park Nottingham

Curated by ChEMBL

LigandBDBM50524096(CHEMBL4455565)Copy SMILESCopy InChI

Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of N-terminal His-tagged truncated human PI3Kbeta (deltaN 1 to 108 residues) after 2 hrs in presence of [33P]ATP by BetaPlate liquid scint...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/24/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
University Park Nottingham

Curated by ChEMBL

LigandBDBM50524096(CHEMBL4455565)Copy SMILESCopy InChI

Affinity DataIC50: 60nMAssay Description:Inhibition of N-terminal His-tagged truncated human PI3Kgamma (deltaN 1 to 108 residues) after 2 hrs in presence of [33P]ATP by BetaPlate liquid scin...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/24/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL