BDBM50524069 CHEMBL4454177

SMILES CC[C@@H](C)C1=C2N=C3OC=CC=C[C@]3(OC)C(=O)N2[C@@H](Cc2ccccc2)C(=O)N1

InChI Key InChIKey=HFZOLZVOTSSKSM-UHFFFAOYSA-N

Data  6 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50524069   

TargetOxysterols receptor LXR-alpha(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50524069(CHEMBL4454177)
Affinity DataEC50:  4.10E+4nMAssay Description:Transactivation of recombinant GAL4-fused human LXRalpha LBD (163 to 447 residues) expressed in human L02 cells measured after 24 hrs by luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50524069(CHEMBL4454177)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant human MEG2 expressed in Escherichia coli using pNPP as substrate preincubated for 15 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50524069(CHEMBL4454177)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant human IDO1 expressed in Escherichia coli using pNPP as substrate preincubated for 15 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50524069(CHEMBL4454177)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant human TCPTP expressed in Escherichia coli using pNPP as substrate preincubated for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50524069(CHEMBL4454177)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant human SHP2 expressed in Escherichia coli using pNPP as substrate preincubated for 15 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50524069(CHEMBL4454177)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant human PTP1B expressed in Escherichia coli using pNPP as substrate preincubated for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50524069(CHEMBL4454177)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant human SHP1 expressed in Escherichia coli using pNPP as substrate preincubated for 15 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed