BDBM50524067 CHEMBL4514865

SMILES C[C@@H]1C(=O)N\C(=C/c2ccccc2)c2nc3c(O)cccc3c(=O)n12

InChI Key InChIKey=JKOZPSNPSQBQCF-UHFFFAOYSA-N

Data  6 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50524067   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50524067(CHEMBL4514865)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant human SHP2 expressed in Escherichia coli using pNPP as substrate preincubated for 15 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50524067(CHEMBL4514865)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant human TCPTP expressed in Escherichia coli using pNPP as substrate preincubated for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50524067(CHEMBL4514865)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant human SHP1 expressed in Escherichia coli using pNPP as substrate preincubated for 15 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50524067(CHEMBL4514865)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant human MEG2 expressed in Escherichia coli using pNPP as substrate preincubated for 15 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50524067(CHEMBL4514865)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant human PTP1B expressed in Escherichia coli using pNPP as substrate preincubated for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50524067(CHEMBL4514865)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant human IDO1 expressed in Escherichia coli using pNPP as substrate preincubated for 15 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50524067(CHEMBL4514865)
Affinity DataEC50:  1.70E+3nMAssay Description:Transactivation of recombinant GAL4-fused human LXRalpha LBD (163 to 447 residues) expressed in human L02 cells measured after 24 hrs by luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed